Human BAZ1A protein (Recombinant) (N-His) (STJP015207)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BAZ1A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | BAZ1A |
| Gene ID | 11177 |
| Uniprot ID | BAZ1A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu549-Arg666 |
Additional Info
| Function | Regulatory subunit of the ATP-dependent ACF-1 and ACF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and slide edge- and center-positioned histone octamers away from their original location on the DNA template to facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template in an ATP-dependent manner. The ACF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the ACF-5 ISWI chromatin remodeling complex. Has a role in sensing the length of DNA which flank nucleosomes, which modulates the nucleosome spacing activity of the ACF-5 ISWI chromatin remodeling complex. Involved in DNA replication and together with SMARCA5/SNF2H is required for replication of pericentric heterochromatin in S-phase. May have a role in nuclear receptor-mediated transcription repression. |
| Protein Name | Bromodomain Adjacent To Zinc Finger Domain Protein 1aAtp-Dependent Chromatin-Remodeling ProteinAtp-Utilizing Chromatin Assembly And Remodeling Factor 1Hacf1Chrac Subunit Acf1Williams Syndrome Transcription Factor-Related Chromatin-Remodeling Factor 180Wcrf180Hwalp1 |
| Database Links | |
| Cellular Localisation | NucleusLocalizes To Pericentric HeterochromatinMay Target The Chrac Complex To HeterochromatinLocalizes To Sites Of Dna Damage |
| Alternative Protein Names | Bromodomain Adjacent To Zinc Finger Domain Protein 1a proteinAtp-Dependent Chromatin-Remodeling Protein proteinAtp-Utilizing Chromatin Assembly And Remodeling Factor 1 proteinHacf1 proteinChrac Subunit Acf1 proteinWilliams Syndrome Transcription Factor-Related Chromatin-Remodeling Factor 180 proteinWcrf180 proteinHwalp1 proteinBAZ1A proteinACF1 proteinWCRF180 proteinHSPC317 protein |
Information sourced from Uniprot.org