Home
Research Area
Signal Transduction
Human B7-1/CD80 protein (Recombinant) (C-His) (STJP002549)

Human B7-1/CD80 protein (Recombinant) (C-His) (STJP002549)

SKU:

STJP002549

£59.50 - £156.50

Current Stock:

General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human B7-1/CD80-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Recombinant human CD80 at 2 Mu g/mL (100 Mu L/well) can bind Recombinant human CTLA-4 with a linear range of 10-50 ng/mL.

Gene Symbol:	CD80
Gene ID:	941
Uniprot ID:	CD80_HUMAN
Immunogen Region:	Val35-Asn242
Immunogen:	Recombinant Human B7-1/CD80 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Val35-Asn242) of human B7-1/CD80 (Accession #NP_005182.1) fused with a 6×His tag at the C-terminus.

Function	Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Protein Name	T-Lymphocyte Activation Antigen Cd80 Activation B7-1 Antigen Bb1 Ctla-4 Counter-Receptor B7.1 B7 Cd Antigen Cd80
Database Links	Reactome: R-HSA-1257604 Reactome: R-HSA-2219530 Reactome: R-HSA-389356 Reactome: R-HSA-389357 Reactome: R-HSA-389359 Reactome: R-HSA-389513 Reactome: R-HSA-6783783 Reactome: R-HSA-6811558
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	T-Lymphocyte Activation Antigen Cd80 protein Activation B7-1 Antigen protein Bb1 protein Ctla-4 Counter-Receptor B7.1 protein B7 protein Cd Antigen Cd80 protein CD80 protein CD28LG protein CD28LG1 protein LAB7 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

reviews