Human ASTL (Astacin Like Metallo Endopeptidase) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013730)

Human ASTL (Astacin Like Metallo Endopeptidase) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013730)

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STJE0013730
£484.50 - £666.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.060ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This ASTL Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ASTL
Gene ID: 431705
Uniprot ID: ASTL_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
Protein Name Astacin-Like Metalloendopeptidase
Oocyte Astacin
Ovastacin
Zp2-Proteinase
Database Links
Cellular Localisation Cytoplasm
Cell Membrane
Cytoplasmic Vesicle
Secretory Vesicle
Cortical Granule
Probably Exocytosed From Cortical Granules During Post-Fertilization
Detected Throughout The Ooplasm Of Germinal Vesicle Stage Oocytes In Early Bilaminar Secondary Follicles At Postnatal (Pn) Day 3
Detected In The Microvillar Domain Of The Oolemma In Arrested Ovulated Secondary Oocytes And In The First Polar Body Prior To Fertilization
Upon Fertilization
Detected In The Perivitelline Space (Pvs) And Occasionally On The Oolemma In 2-Cell Through Morulae Stages
Colocalizes With Spaca3 At The Microvillar Domain Of The Oolemma And In The Perivitelline Space (Pvs)
Alternative ELISA Names Astacin-Like Metalloendopeptidase ELISA kit
Oocyte Astacin ELISA kit
Ovastacin ELISA kit
Zp2-Proteinase ELISA kit
ASTL ELISA kit
output

Information sourced from Uniprot.org

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