Human ASS1 protein (Recombinant) (N-His) (STJP003497)

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STJP003497
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ASS1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ASS1
Gene ID: 445
Uniprot ID: ASSY_HUMAN
Immunogen Region: Glu149-Lys412
Immunogen: Homo sapiens (Human)
Post Translational Modifications Acetylated by CLOCK in a circadian manner which negatively regulates its enzyme activity. Deacetylated by histone deacetylases.
Function One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Protein Name Argininosuccinate Synthase
Citrulline--Aspartate Ligase
Database Links Reactome: R-HSA-70635
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Argininosuccinate Synthase protein
Citrulline--Aspartate Ligase protein
ASS1 protein
ASS protein

Information sourced from Uniprot.org

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