Human ASGR2 protein (Recombinant) (N-His) (STJP003782)

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STJP003782
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ASGR2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ASGR2
Gene ID: 433
Uniprot ID: ASGR2_HUMAN
Immunogen Region: Met1-Ala311
Immunogen: Homo sapiens (Human)
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Protein Name Asialoglycoprotein Receptor 2
Asgp-R 2
Asgpr 2
C-Type Lectin Domain Family 4 Member H2
Hepatic Lectin H2
Hl-2
Database Links Reactome: R-HSA-446203
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Asialoglycoprotein Receptor 2 protein
Asgp-R 2 protein
Asgpr 2 protein
C-Type Lectin Domain Family 4 Member H2 protein
Hepatic Lectin H2 protein
Hl-2 protein
ASGR2 protein
CLEC4H2 protein

Information sourced from Uniprot.org

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