Human ASGR1 protein (Recombinant) (N-Fc) (STJP007259)

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STJP007259
€586.88 - €3,115.63
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ASGR1-N-Fc protein was developed from mammalian cells and has a target region of N-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ASGR1
Gene ID: 432
Uniprot ID: ASGR1_HUMAN
Immunogen Region: Gln62-Leu291
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated on a cytoplasmic Ser residue.
Function Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Protein Name Asialoglycoprotein Receptor 1
Asgp-R 1
Asgpr 1
C-Type Lectin Domain Family 4 Member H1
Hepatic Lectin H1
Hl-1
Database Links Reactome: R-HSA-446203
Cellular Localisation Isoform H1a: Membrane
Single-Pass Type Ii Membrane Protein
Isoform H1b: Secreted
Alternative Protein Names Asialoglycoprotein Receptor 1 protein
Asgp-R 1 protein
Asgpr 1 protein
C-Type Lectin Domain Family 4 Member H1 protein
Hepatic Lectin H1 protein
Hl-1 protein
ASGR1 protein
CLEC4H1 protein

Information sourced from Uniprot.org

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