Human ASGR1 protein (Recombinant) (C-His) (STJP013120)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ASGR1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.2. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | ASGR1 |
| Gene ID | 432 |
| Uniprot ID | ASGR1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln62-Leu291 |
Additional Info
| Post Translational Modifications | Phosphorylated on a cytoplasmic Ser residue. |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Protein Name | Asialoglycoprotein Receptor 1Asgp-R 1Asgpr 1C-Type Lectin Domain Family 4 Member H1Hepatic Lectin H1Hl-1 |
| Database Links | Reactome: R-HSA-446203 |
| Cellular Localisation | Isoform H1a: MembraneSingle-Pass Type Ii Membrane ProteinIsoform H1b: Secreted |
| Alternative Protein Names | Asialoglycoprotein Receptor 1 proteinAsgp-R 1 proteinAsgpr 1 proteinC-Type Lectin Domain Family 4 Member H1 proteinHepatic Lectin H1 proteinHl-1 proteinASGR1 proteinCLEC4H1 protein |
Information sourced from Uniprot.org