SDS-PAGE of recombinant human ASCC1 protein 3μg under reducing conditions with Coomassie blue stain

Human ASCC1 protein (Recombinant) (His-Tag) (STJP018406)

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STJP018406
£134.50 - £738.50
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Short Description :Recombinant-Human ASCC1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:ASCC1
Gene ID:51008
Uniprot ID:ASCC1_HUMAN
Accession Number:NP_001185727
Immunogen:Human
Immunogen Region:1-357aa
Immunogen Sequence:MEVLRPQ LIRIDGRNYR KNPVQEQTYQ HEEDEEDFYQ GSMECADEPC DAYEVEQTPQ GFRSTLRAPS LLYKHIVGKR GDTRKKIEME TKTSISIPKP GQDGEIVITG QHRNGVISAR TRIDVLLDTF RRKQPFTHFL AFFLNEVEVQ EGFLRFQEEV LAKCSMDHGV DSSIFQNPKK LHLTIGMLVL LSEEEIQQTC EMLQQC
Tissue Specificity Ubiquitous.
Function Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction.
Protein Name Activating Signal Cointegrator 1 Complex Subunit 1
Asc-1 Complex Subunit P50
Trip4 Complex Subunit P50
Database Links Reactome: R-HSA-112126
Cellular Localisation Nucleus
Nucleus Speckle
Colocalizes With Prpf8 In Nuclear Speckles In The Absence Of Dna Damage
Alternative Protein Names Activating Signal Cointegrator 1 Complex Subunit 1 protein
Asc-1 Complex Subunit P50 protein
Trip4 Complex Subunit P50 protein
ASCC1 protein
CGI-18 protein

Information sourced from Uniprot.org

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