| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ARF4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 5mM DTT, 20% Glycerol |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARF4 |
| Gene ID: | 378 |
| Uniprot ID: | ARF4_HUMAN |
| Immunogen Region: | 1-180aa |
| Accession Number: | NP_001651 |
| Immunogen: | Human |
| Immunogen Sequence: |
| Function | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking.may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation. |
| Protein Name | Adp-Ribosylation Factor 4 |
| Database Links | Reactome: R-HSA-5620916Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Golgi ApparatusMembraneLipid-Anchor |
| Alternative Protein Names | Adp-Ribosylation Factor 4 proteinARF4 proteinARF2 protein |
Information sourced from Uniprot.org