| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.054ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This AQP9 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | AQP9 |
| Gene ID: | 366 |
| Uniprot ID: | AQP9_HUMAN |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. |
| Post Translational Modifications | |
| Function | Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. AQP9 is the primary route for glycerol uptake in hepatocytes, supporting hepatic gluconeogenesis. It exhibits broad specificity and may transport various small, non-charged solutes, including carbamides, polyols, purines, and pyrimidines. AQP9 may also facilitate hepatic urea extrusion. Due to its permeability to lactate, AQP9 might participate in the astrocyte-to-neuron lactate shuttle, supplying neurons with energy. Additionally, AQP9 is permeable to arsenite, contributing to arsenic excretion by the liver and providing partial protection against arsenic toxicity. It is also permeable to H2O2 in vivo. Could also be permeable to ammonium. |
| Protein Name | Aquaporin-9 Aqp-9 Aquaglyceroporin-9 Small Solute Channel 1 |
| Database Links | Reactome: R-HSA-432030 Reactome: R-HSA-432047 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Functions At The Hepatocyte Basolateral Membrane |
| Alternative ELISA Names | Aquaporin-9 ELISA kit Aqp-9 ELISA kit Aquaglyceroporin-9 ELISA kit Small Solute Channel 1 ELISA kit AQP9 ELISA kit SSC1 ELISA kit |
| output |
Information sourced from Uniprot.org