Human AQP5 (Aquaporin 5) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013663)

Human AQP5 (Aquaporin 5) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013663)

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STJE0013663
£446.50 - £611.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.141ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This AQP5 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: AQP5
Gene ID: 362
Uniprot ID: AQP5_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in skin eccrine sweat glands, at the apical cell membrane and at intercellular canaliculi (at protein level).
Post Translational Modifications
Function Aquaporins form homotetrameric transmembrane channels, with each monomer independently mediating water transport across the plasma membrane along its osmotic gradient. Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands.
Protein Name Aquaporin-5
Aqp-5
Database Links Reactome: R-HSA-432047
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Cytoplasmic Vesicle Membrane
Hypotonicity Increases Location At The Cell Membrane
Phosphorylation Decreases Location At The Cell Membrane
Alternative ELISA Names Aquaporin-5 ELISA kit
Aqp-5 ELISA kit
AQP5 ELISA kit
output

Information sourced from Uniprot.org

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