| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.01 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | APOA4 |
| Gene ID: | 337 |
| Uniprot ID: | APOA4_HUMAN |
| Immunogen Region: | Glu21-Ser396 |
| Immunogen: | Recombinant Human Apolipoprotein A-IV/APOA4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu21-Ser396) ofHuman Apolipoprotein A-IV/APOA4 (Accession #NP_000473.2) fused with a His tag at the C-t |
| Immunogen Sequence: | EVSADQVATVMWDYFSQLSN NAKEAVEHLQKSELTQQLNA LFQDKLGEVNTYAGDLQKKL VPFATELHERLAKDSEKLKE EIGKELEELRARLLPHANEV SQKIGDNLRELQQRLEPYAD QLRTQVSTQAEQLRRQLTPY AQRMERVLRENADSLQASLR PHADELKAKIDQNVEELKGR LTPYADEFKVKIDQTVEELR RSLAPYAQDTQEKLNHQLEG LTFQMKKNAEELKARISAS |
| Post Translational Modifications | Phosphorylation sites are present in the extracellular medium. |
| Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II.potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
| Protein Name | Apolipoprotein A-IvApo-AivApoa-IvApolipoprotein A4 |
| Database Links | Reactome: R-HSA-8963888Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-975634Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Apolipoprotein A-Iv proteinApo-Aiv proteinApoa-Iv proteinApolipoprotein A4 proteinAPOA4 protein |
Information sourced from Uniprot.org
