Human APOA5 (APOA5) Sandwich ELISA Kit Kit (STJE0000278)

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STJE0000278-96
€549.38
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056 ng/mL
Detection Limit: 031-20 ng/ml
Conjugation: Biotin
Storage Instruction: Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month.
Assay Time: 3 hours
Detection: Colorimetric
Gene Symbol: APOA5
Gene ID: 116519
Uniprot ID: APOA5_HUMAN
Sample Type: serum, plasma and cell culture supernates
Tissue Specificity Liver and plasma.
Post Translational Modifications Phosphorylated by FAM20C in the extracellular medium.
Function Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin.
Protein Name Apolipoprotein A-V
Apo-Av
Apoa-V
Apolipoprotein A5
Regeneration-Associated Protein 3
Database Links Reactome: R-HSA-1989781
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-8963889
Reactome: R-HSA-8963901
Cellular Localisation Secreted
Early Endosome
Late Endosome
Golgi Apparatus
Trans-Golgi Network
In The Presence Of Sorl1
Internalized To Early Endosomes
Sorted In A Retrograde Fashion To Late Endosomes
From Which A Portion Is Sent To Lysosomes And Degradation
Another Portion Is Sorted To The Trans-Golgi Network
Alternative ELISA Names Apolipoprotein A-V ELISA kit
Apo-Av ELISA kit
Apoa-V ELISA kit
Apolipoprotein A5 ELISA kit
Regeneration-Associated Protein 3 ELISA kit
APOA5 ELISA kit
RAP3 ELISA kit
UNQ411 ELISA kit
PRO773 ELISA kit
output

Information sourced from Uniprot.org

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