Function | This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. Also, involved in the degradation of oxidized and glycated proteins. |
Protein Name | Acylamino-Acid-Releasing EnzymeAareAcyl-Peptide HydrolaseAphAcylaminoacyl-PeptidaseOxidized Protein HydrolaseOph |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-72764 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Acylamino-Acid-Releasing Enzyme proteinAare proteinAcyl-Peptide Hydrolase proteinAph proteinAcylaminoacyl-Peptidase proteinOxidized Protein Hydrolase proteinOph proteinAPEH proteinD3F15S2 proteinD3S48E proteinDNF15S2 protein |
Information sourced from Uniprot.org