| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human APBB1IP-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | APBB1IP |
| Gene ID: | 54518 |
| Uniprot ID: | AB1IP_HUMAN |
| Immunogen Region: | Lys177-Gly420 |
| Immunogen: | Homo sapiens (Human) |
| Function | Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion. |
| Protein Name | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting ProteinApbb1-Interacting Protein 1Proline-Rich Evh1 Ligand 1Prel-1Proline-Rich Protein 73Rap1-Gtp-Interacting Adapter MoleculeRiamRetinoic Acid-Responsive Proline-Rich Protein 1Rarp-1 |
| Database Links | Reactome: R-HSA-354192Reactome: R-HSA-354194Reactome: R-HSA-372708Reactome: R-HSA-5674135Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-9649948Reactome: R-HSA-9656223 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCell ProjectionLamellipodiumCell JunctionFocal AdhesionCytoplasmCytoskeletonColocalizes With Ena/Vasp Proteins At Lamellipodia Tips And Focal AdhesionsAnd F-Actin At The Leading EdgeAt The Membrane SurfaceAssociatesVia The Ph DomainPreferentially With The Inositol PhosphatesPtdins(5)P And Ptdins(3)PThis Binding Appears To Be Necessary For The Efficient Interaction Of The Ra Domain To Ras-Gtpases |
| Alternative Protein Names | Amyloid Beta A4 Precursor Protein-Binding Family B Member 1-Interacting Protein proteinApbb1-Interacting Protein 1 proteinProline-Rich Evh1 Ligand 1 proteinPrel-1 proteinProline-Rich Protein 73 proteinRap1-Gtp-Interacting Adapter Molecule proteinRiam proteinRetinoic Acid-Responsive Proline-Rich Protein 1 proteinRarp-1 proteinAPBB1IP proteinPREL1 proteinRARP1 proteinRIAM protein |
Information sourced from Uniprot.org