Post Translational Modifications | Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. |
Function | Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for 2-phenylethylamine, tryptamine and tyramine. Could also act on methylamine and benzylamine but much less efficiently. |
Protein Name | Amine Oxidase Copper-Containing 2Amine Oxidase Copper-Containing 2Retina-Specific Copper Amine OxidaseRaoSemicarbazide-Sensitive Amine OxidaseSsao |
Database Links | Reactome: R-HSA-211945 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2: CytoplasmEither Not Translocated To The Plasma Membrane Or Below Detection Level |
Alternative Protein Names | Amine Oxidase Copper-Containing 2 proteinAmine Oxidase Copper-Containing 2 proteinRetina-Specific Copper Amine Oxidase proteinRao proteinSemicarbazide-Sensitive Amine Oxidase proteinSsao proteinAOC2 protein |
Information sourced from Uniprot.org