Name: Human ANTXR2 protein (Recombinant) (N-His) (STJP004993)
SKU: STJP004993
Availability: InStock

Human ANTXR2 protein (Recombinant) (N-His) (STJP004993)

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STJP004993

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ANTXR2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Necessary for cellular interactions with laminin and the extracellular matrix. (Microbial infection) Receptor for the protective antigen (PA) of B.anthracis. Binding of PA leads to heptamerization of the receptor-PA complex. Upon binding of the PA of B.anthracis, the complex moves to glycosphingolipid-rich lipid rafts, where it is internalized via a clathrin-dependent pathway. In the endosomal membrane, at pH under 7, the complex then rearranges and forms a pore allowing the other components of anthrax toxin to escape to the cytoplasm.
Protein Name	Anthrax Toxin Receptor 2 Capillary Morphogenesis Gene 2 Protein Cmg-2
Database Links	Reactome: R-HSA-5210891
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Expressed At The Cell Surface Isoform 2: Endoplasmic Reticulum Membrane Expressed Predominantly Within The Endoplasmic Reticulum And Not At The Plasma Membrane Isoform 3: Secreted
Alternative Protein Names	Anthrax Toxin Receptor 2 protein Capillary Morphogenesis Gene 2 Protein protein Cmg-2 protein ANTXR2 protein CMG2 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP009178	Mouse ANTXR2 protein (Recombinant) (N-His) (STJP009178)	E. coli
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP002980	Human KLHL20 protein (Recombinant) (N-His) (STJP002980)	HEK293 cells
STJP003027	Human CCL3L1 protein (Recombinant) (N-His) (STJP003027)	HEK293 cells

Human ANTXR2 protein (Recombinant) (N-His) (STJP004993)

General Information