Human ANO2 protein (Recombinant) (N-His) (STJP009722)

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STJP009722
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ANO2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ANO2
Gene ID: 57101
Uniprot ID: ANO2_HUMAN
Immunogen Region: Arg188-Ala365
Immunogen: Homo sapiens (Human)
Function Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Protein Name Anoctamin-2
Transmembrane Protein 16b
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-381753
Reactome: R-HSA-9733458
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Anoctamin-2 protein
Transmembrane Protein 16b protein
ANO2 protein
C12orf3 protein
TMEM16B protein

Information sourced from Uniprot.org