| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human AMOTL1-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | AMOTL1 |
| Gene ID: | 154810 |
| Uniprot ID: | AMOL1_HUMAN |
| Immunogen Region: | Gly96-Thr141 |
| Immunogen: | Homo sapiens (Human) |
| Function | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
| Protein Name | Angiomotin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2028269 |
| Cellular Localisation | Cell JunctionTight Junction |
| Alternative Protein Names | Angiomotin-Like Protein 1 proteinAMOTL1 protein |
Information sourced from Uniprot.org