Human AMN (Amnionless) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013482)

Human AMN (Amnionless) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013482)

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STJE0013482
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.107ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This AMN Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: AMN
Gene ID: 81693
Uniprot ID: AMNLS_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in proximal tubules in the kidney cortex (at protein level). Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes.
Post Translational Modifications N-glycosylated. A soluble form arises by proteolytic removal of the membrane anchor.
Function Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney (Probable).
Protein Name Protein Amnionless Cleaved Into - Soluble Protein Amnionless
Database Links Reactome: R-HSA-3359462
Reactome: R-HSA-3359463
Reactome: R-HSA-8964011
Reactome: R-HSA-9758881
Cellular Localisation Isoform 1: Apical Cell Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Endosome Membrane
Membrane
Coated Pit
Soluble Protein Amnionless: Secreted
Alternative ELISA Names Protein Amnionless Cleaved Into - Soluble Protein Amnionless ELISA kit
AMN ELISA kit
UNQ513 ELISA kit
PRO1028 ELISA kit
output

Information sourced from Uniprot.org

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