Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
Protein Name | Amphoterin-Induced Protein 2Amigo-2Alivin-1Differentially Expressed In Gastric AdenocarcinomasDega |
Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleusAssociated With Nucleus As Well As Plasma MembraneRestricted To Somata Of Cerebellar As Well As Hippocampal Neurons |
Alternative Protein Names | Amphoterin-Induced Protein 2 proteinAmigo-2 proteinAlivin-1 proteinDifferentially Expressed In Gastric Adenocarcinomas proteinDega proteinAMIGO2 proteinALI1 protein |
Information sourced from Uniprot.org