Human AMIGO2 protein (Recombinant) (C-His) (STJP013514)

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STJP013514-100
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Host: Mammalian Cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AMIGO2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: AMIGO2
Gene ID: 347902
Uniprot ID: AMGO2_HUMAN
Immunogen Region: Gly40-His393
Immunogen: Homo sapiens (Human)
Function Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
Protein Name Amphoterin-Induced Protein 2
Amigo-2
Alivin-1
Differentially Expressed In Gastric Adenocarcinomas
Dega
Database Links Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Nucleus
Associated With Nucleus As Well As Plasma Membrane
Restricted To Somata Of Cerebellar As Well As Hippocampal Neurons
Alternative Protein Names Amphoterin-Induced Protein 2 protein
Amigo-2 protein
Alivin-1 protein
Differentially Expressed In Gastric Adenocarcinomas protein
Dega protein
AMIGO2 protein
ALI1 protein

Information sourced from Uniprot.org

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