| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.054ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This ALK1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | ACVRL1 |
| Gene ID: | 94 |
| Uniprot ID: | ACVL1_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Protein Name | Activin Receptor Type-1-Like Activin Receptor-Like Kinase 1 Alk-1 Serine/Threonine-Protein Kinase Receptor R3 Skr3 Tgf-B Superfamily Receptor Type I Tsr-I |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative ELISA Names | Activin Receptor Type-1-Like ELISA kit Activin Receptor-Like Kinase 1 ELISA kit Alk-1 ELISA kit Serine/Threonine-Protein Kinase Receptor R3 ELISA kit Skr3 ELISA kit Tgf-B Superfamily Receptor Type I ELISA kit Tsr-I ELISA kit ACVRL1 ELISA kit ACVRLK1 ELISA kit ALK1 ELISA kit |
| output |
Information sourced from Uniprot.org