Human ALK1 (Activin Receptor Like Kinase 1) Sandwich ELISA Kit (STJE0007076)
SPECIFICATIONS
General Information
| Short Description | This ALK1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.054ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | ACVRL1 |
| Gene ID | 94 |
| Uniprot ID | ACVL1_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Protein Name | Activin Receptor Type-1-LikeActivin Receptor-Like Kinase 1Alk-1Serine/Threonine-Protein Kinase Receptor R3Skr3Tgf-B Superfamily Receptor Type ITsr-I |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Activin Receptor Type-1-Like ELISA kitActivin Receptor-Like Kinase 1 ELISA kitAlk-1 ELISA kitSerine/Threonine-Protein Kinase Receptor R3 ELISA kitSkr3 ELISA kitTgf-B Superfamily Receptor Type I ELISA kitTsr-I ELISA kitACVRL1 ELISA kitACVRLK1 ELISA kitALK1 ELISA kit |
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Information sourced from Uniprot.org