Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light. |
Protein Name | Aldehyde Dehydrogenase - Dimeric Nadp-PreferringAldhiiiAldehyde Dehydrogenase 3Aldehyde Dehydrogenase Family 3 Member A1 |
Database Links | Reactome: R-HSA-211945 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Aldehyde Dehydrogenase - Dimeric Nadp-Preferring proteinAldhiii proteinAldehyde Dehydrogenase 3 proteinAldehyde Dehydrogenase Family 3 Member A1 proteinALDH3A1 proteinALDH3 protein |
Information sourced from Uniprot.org