Human AKR1B10 protein (Recombinant) (N-His) (STJP003301)

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STJP003301
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AKR1B10-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AKR1B10
Gene ID: 57016
Uniprot ID: AK1BA_HUMAN
Immunogen Region: Met1-Tyr316
Immunogen: Homo sapiens (Human)
Function Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose.
Protein Name Aldo-Keto Reductase Family 1 Member B10
Arl-1
Aldose Reductase-Like
Aldose Reductase-Related Protein
Arp
Harp
Small Intestine Reductase
Si Reductase
Database Links Reactome: R-HSA-975634
Cellular Localisation Lysosome
Secreted
Secreted Through A Lysosome-Mediated Non-Classical Pathway
Alternative Protein Names Aldo-Keto Reductase Family 1 Member B10 protein
Arl-1 protein
Aldose Reductase-Like protein
Aldose Reductase-Related Protein protein
Arp protein
Harp protein
Small Intestine Reductase protein
Si Reductase protein
AKR1B10 protein
AKR1B11 protein

Information sourced from Uniprot.org

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