| Host: | E.coli |
| Applications: | SDS-PAGE |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human AIDA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.2M NaCl, 1mM DTT |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AIDA |
| Gene ID: | 64853 |
| Uniprot ID: | AIDA_HUMAN |
| Immunogen Region: | 1-306aa |
| Accession Number: | NP_073742 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSEVTRS LLQRWGASFR RGADFDSWGQ LVEAIDEYQI LARHLQKEAQ AQHNNSEFTE EQKKTIGKIA TCLELRSAAL QSTQSQEEFK LEDLKKLEPI LKNILTYNKE FPFDVQPVPL RRILAPGEEE NLEFEEDEEE GGAGAGSPDS FPARVPGTLL PRLPSEPGMT LLTIRIEKIG LKDAGQCIDP YITVSVKDLN GIDLTPVQ |
| Tissue Specificity | Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle. |
| Function | Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. |
| Protein Name | Axin Interactor - Dorsalization-Associated ProteinAxin Interaction Partner And Dorsalization Antagonist |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Axin Interactor - Dorsalization-Associated Protein proteinAxin Interaction Partner And Dorsalization Antagonist proteinAIDA proteinC1orf80 protein |
Information sourced from Uniprot.org