| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human AGTRAP-N-His-SUMO protein was developed from e.coli and has a target region of N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | AGTRAP |
| Gene ID: | 57085 |
| Uniprot ID: | ATRAP_HUMAN |
| Immunogen Region: | His108-Tyr159 |
| Immunogen: | Homo sapiens (Human) |
| Function | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Also induces a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
| Protein Name | Type-1 Angiotensin Ii Receptor-Associated ProteinAt1 Receptor-Associated Protein |
| Database Links | Reactome: R-HSA-6802952 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCytoplasmic Vesicle MembranePresent In Perinuclear Vesicular MembranesEndoplasmic ReticulumGolgi And Endocytic Vesicles |
| Alternative Protein Names | Type-1 Angiotensin Ii Receptor-Associated Protein proteinAt1 Receptor-Associated Protein proteinAGTRAP proteinATRAP protein |
Information sourced from Uniprot.org