Human AGTRAP protein (Recombinant) (N-His-SUMO) (STJP008973)

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STJP008973
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human AGTRAP-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: AGTRAP
Gene ID: 57085
Uniprot ID: ATRAP_HUMAN
Immunogen Region: His108-Tyr159
Immunogen: Homo sapiens (Human)
Function Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Protein Name Type-1 Angiotensin Ii Receptor-Associated Protein
At1 Receptor-Associated Protein
Database Links Reactome: R-HSA-6802952
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Cytoplasmic Vesicle Membrane
Present In Perinuclear Vesicular Membranes
Endoplasmic Reticulum
Golgi And Endocytic Vesicles
Alternative Protein Names Type-1 Angiotensin Ii Receptor-Associated Protein protein
At1 Receptor-Associated Protein protein
AGTRAP protein
ATRAP protein

Information sourced from Uniprot.org

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