Human AGA protein (Recombinant) (His-Tag) (STJP019064)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human AGA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AGA |
| Gene ID | 175 |
| Uniprot ID | ASPG_HUMAN |
| Accession Number | NP_000018 |
| Immunogen | Human |
| Immunogen Region | 24-346aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSSSPLPLV VNTWPFKNAT EAAWRALASG GSALDAVESG CAMCEREQCD GSVGFGGSPD ELGETTLDAM IMDGTTMDVG AVGDLRRIKN AIGVARKVLE HTTHTLLVGE SATTFAQSMG FINEDLSTTA SQALHSDWLA RNCQPNYWRN VIPDPSKYCG PYKPPGILKQ DIPIHKETED DRGHDTIGMV VIHKTGHIAA GTSTNGIK |
Additional Info
| Post Translational Modifications | Cleaved into an alpha and beta chain by autocatalysis.this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity. N-glycosylated. |
| Function | Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. |
| Protein Name | N(4-(Beta-N-Acetylglucosaminyl-L-AsparaginaseAspartylglucosaminidaseGlycosylasparaginaseN4-(N-Acetyl-Beta-Glucosaminyl-L-Asparagine Amidase Cleaved Into - Glycosylasparaginase Alpha Chain - Glycosylasparaginase Beta Chain |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Lysosome |
| Alternative Protein Names | N(4-(Beta-N-Acetylglucosaminyl-L-Asparaginase proteinAspartylglucosaminidase proteinGlycosylasparaginase proteinN4-(N-Acetyl-Beta-Glucosaminyl-L-Asparagine Amidase Cleaved Into - Glycosylasparaginase Alpha Chain - Glycosylasparaginase Beta Chain proteinAGA protein |
Information sourced from Uniprot.org