Tissue Specificity | Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary. |
Post Translational Modifications | |
Function | Intermedin/ADM2 is a peptide hormone that plays a role as physiological regulator of gastrointestinal and cardiovascular bioactivities mediated by the CALCRL-RAMPs receptor complexes. Activates the cAMP-dependent pathway through interaction with CALCRL-RAMP3 receptor complex. |
Protein Name | Protein Adm2Intermedin Cleaved Into - Adrenomedullin-2Am2Intermedin-LongImdl - Intermedin-ShortImds |
Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Protein Adm2 ELISA kitIntermedin Cleaved Into - Adrenomedullin-2 ELISA kitAm2 ELISA kitIntermedin-Long ELISA kitImdl - Intermedin-Short ELISA kitImds ELISA kitADM2 ELISA kitAM2 ELISA kit |
output | |
Information sourced from Uniprot.org