Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. |
Protein Name | Adiponectin Receptor Protein 2Progestin And Adipoq Receptor Family Member 2Progestin And Adipoq Receptor Family Member Ii |
Database Links | Reactome: R-HSA-163680 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized To The Cell Membrane And Intracellular Organelles |
Alternative Protein Names | Adiponectin Receptor Protein 2 proteinProgestin And Adipoq Receptor Family Member 2 proteinProgestin And Adipoq Receptor Family Member Ii proteinADIPOR2 proteinPAQR2 protein |
Information sourced from Uniprot.org