| Tissue Specificity | Preferentially expressed in stomach. |
| Post Translational Modifications | |
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh7Alcohol Dehydrogenase Class 4 Mu/Sigma ChainAlcohol Dehydrogenase Class Iv Mu/Sigma ChainGastric Alcohol DehydrogenaseOmega-Hydroxydecanoate Dehydrogenase Adh7Retinol Dehydrogenase |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | All-Trans-Retinol Dehydrogenase Nad(+ Adh7 ELISA kitAlcohol Dehydrogenase Class 4 Mu/Sigma Chain ELISA kitAlcohol Dehydrogenase Class Iv Mu/Sigma Chain ELISA kitGastric Alcohol Dehydrogenase ELISA kitOmega-Hydroxydecanoate Dehydrogenase Adh7 ELISA kitRetinol Dehydrogenase ELISA kitADH7 ELISA kit |
| output | |
Information sourced from Uniprot.org
