Human ADGRL1 protein (Recombinant) (N-His) (STJP010769)

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STJP010769
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ADGRL1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADGRL1
Gene ID: 22859
Uniprot ID: AGRL1_HUMAN
Immunogen Region: Gly142-Gly397
Immunogen: Homo sapiens (Human)
Function Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis.
Protein Name Adhesion G Protein-Coupled Receptor L1
Calcium-Independent Alpha-Latrotoxin Receptor 1
Cirl-1
Latrophilin-1
Lectomedin-2
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Axon
Growth Cone
Synapse
Presynaptic Cell Membrane
Synaptosome
Colocalizes With Tenm2 On The Cell Surface
Across Intercellular Junctions And On Nerve Terminals Near Synaptic Clefts
Alternative Protein Names Adhesion G Protein-Coupled Receptor L1 protein
Calcium-Independent Alpha-Latrotoxin Receptor 1 protein
Cirl-1 protein
Latrophilin-1 protein
Lectomedin-2 protein
ADGRL1 protein
KIAA0821 protein
LEC2 protein
LPHN1 protein

Information sourced from Uniprot.org

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