| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ADCY2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ADCY2 |
| Gene ID: | 108 |
| Uniprot ID: | ADCY2_HUMAN |
| Immunogen Region: | Ala294-Thr525 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Phosphorylated by RAF1. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors. |
| Protein Name | Adenylate Cyclase Type 2Atp Pyrophosphate-Lyase 2Adenylate Cyclase Type IiAdenylyl Cyclase 2 |
| Database Links | Reactome: R-HSA-163359Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-170660Reactome: R-HSA-170670Reactome: R-HSA-418555Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-432040Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasm |
| Alternative Protein Names | Adenylate Cyclase Type 2 proteinAtp Pyrophosphate-Lyase 2 proteinAdenylate Cyclase Type Ii proteinAdenylyl Cyclase 2 proteinADCY2 proteinKIAA1060 protein |
Information sourced from Uniprot.org