Human ADAMTS1 protein (Recombinant) (N-His) (STJP006162)

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STJP006162
£328.50 - £1,437.50
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ADAMTS1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADAMTS1
Gene ID: 9510
Uniprot ID: ATS1_HUMAN
Immunogen Region: Arg258-Pro467
Immunogen: Homo sapiens (Human)
Function Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
Protein Name A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1
Adam-Ts 1
Adam-Ts1
Adamts-1
Meth-1
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-5083635
Reactome: R-HSA-5173214
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names A Disintegrin And Metalloproteinase With Thrombospondin Motifs 1 protein
Adam-Ts 1 protein
Adam-Ts1 protein
Adamts-1 protein
Meth-1 protein
ADAMTS1 protein
KIAA1346 protein
METH1 protein

Information sourced from Uniprot.org

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