Human ADAM19 protein (Recombinant) (N-His) (STJP006421)

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STJP006421
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human ADAM19-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADAM19
Gene ID: 8728
Uniprot ID: ADA19_HUMAN
Immunogen Region: Gly326-Ser699
Immunogen: Homo sapiens (Human)
Post Translational Modifications The precursor is cleaved by a furin endopeptidase.
Function Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone.
Protein Name Disintegrin And Metalloproteinase Domain-Containing Protein 19
Adam 19
Meltrin-Beta
Metalloprotease And Disintegrin Dendritic Antigen Marker
Maddam
Database Links Reactome: R-HSA-8941237
Reactome: R-HSA-9762292
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Disintegrin And Metalloproteinase Domain-Containing Protein 19 protein
Adam 19 protein
Meltrin-Beta protein
Metalloprotease And Disintegrin Dendritic Antigen Marker protein
Maddam protein
ADAM19 protein
MLTNB protein
FKSG34 protein

Information sourced from Uniprot.org

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