Tissue Specificity | Expressed in many normal organ tissues and several cancer cell lines. |
Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
Function | Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone. |
Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 19Adam 19Meltrin-BetaMetalloprotease And Disintegrin Dendritic Antigen MarkerMaddam |
Database Links | Reactome: R-HSA-8941237Reactome: R-HSA-9762292 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative ELISA Names | Disintegrin And Metalloproteinase Domain-Containing Protein 19 ELISA kitAdam 19 ELISA kitMeltrin-Beta ELISA kitMetalloprotease And Disintegrin Dendritic Antigen Marker ELISA kitMaddam ELISA kitADAM19 ELISA kitMLTNB ELISA kitFKSG34 ELISA kit |
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Information sourced from Uniprot.org