| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human ACTL7A-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | ACTL7A |
| Gene ID: | 10881 |
| Uniprot ID: | ACL7A_HUMAN |
| Immunogen Region: | Val72-Phe435 |
| Immunogen: | Homo sapiens (Human) |
| Function | Essential for normal spermatogenesis and male fertility. Required for normal sperm head morphology, acroplaxome formation, acrosome attachment, and acrosome granule stability. May anchor and stabilize acrosomal adherence to the acroplaxome at least in part by facilitating the presence of F-actin in the subacrosomal space. May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis. |
| Protein Name | Actin-Like Protein 7aActin-Like-7-Alpha |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonGolgi ApparatusNucleusCytoplasmic VesicleSecretory VesicleAcrosomeDetected At The Golgi Apparatus During Acrosome BiogenesisDetected At The Subacrosomal Layer In Round SpermatidsDetected In Sperm Head And Tail |
| Alternative Protein Names | Actin-Like Protein 7a proteinActin-Like-7-Alpha proteinACTL7A protein |
Information sourced from Uniprot.org