Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. |
Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 6Arachidonate--Coa LigaseLong-Chain Acyl-Coa Synthetase 6Lacs 6 |
Database Links | Reactome: R-HSA-75876 |
Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iii Membrane ProteinPeroxisome MembraneMicrosome MembraneEndoplasmic Reticulum Membrane |
Alternative Protein Names | Long-Chain-Fatty-Acid--Coa Ligase 6 proteinArachidonate--Coa Ligase proteinLong-Chain Acyl-Coa Synthetase 6 proteinLacs 6 proteinACSL6 proteinACS2 proteinFACL6 proteinKIAA0837 proteinLACS5 protein |
Information sourced from Uniprot.org