| Function | Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains. |
| Protein Name | Short-Chain Specific Acyl-Coa Dehydrogenase - MitochondrialScadButyryl-Coa Dehydrogenase |
| Database Links | Reactome: R-HSA-77350Reactome: R-HSA-77352 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Short-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial proteinScad proteinButyryl-Coa Dehydrogenase proteinACADS protein |
Information sourced from Uniprot.org