| Short Description : | Recombinant-Human ABCB5-N-Trx protein was developed from e.coli and has a target region of N-Trx. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | ABCB5 |
| Gene ID: | 340273 |
| Uniprot ID: | ABCB5_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ile141-Val247 |
| Function | Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. |
| Protein Name | Atp-Binding Cassette Sub-Family B Member 5Abcb5 P-GpP-Glycoprotein Abcb5 |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Atp-Binding Cassette Sub-Family B Member 5 proteinAbcb5 P-Gp proteinP-Glycoprotein Abcb5 proteinABCB5 protein |
Information sourced from Uniprot.org