| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.062ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This AADAT Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | AADAT |
| Gene ID: | 51166 |
| Uniprot ID: | AADAT_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary. |
| Post Translational Modifications | |
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Protein Name | Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial Kat/Aadat 2-Aminoadipate Aminotransferase 2-Aminoadipate Transaminase Alpha-Aminoadipate Aminotransferase Aadat Glycine Transaminase Aadat Kynurenine Aminotransferase Ii Kynurenine--Glyoxylate Transaminase Aadat Kynurenine--Oxoglutarate Aminotransferase Ii Kynurenine--Oxoglutarate Transaminase 2 Kynurenine--Oxoglutarate Transaminase Ii Methionine--Glyoxylate Transaminase Aadat |
| Database Links | Reactome: R-HSA-71064 Reactome: R-HSA-71240 |
| Cellular Localisation | Mitochondrion |
| Alternative ELISA Names | Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial ELISA kit Kat/Aadat ELISA kit 2-Aminoadipate Aminotransferase ELISA kit 2-Aminoadipate Transaminase ELISA kit Alpha-Aminoadipate Aminotransferase ELISA kit Aadat ELISA kit Glycine Transaminase Aadat ELISA kit Kynurenine Aminotransferase Ii ELISA kit Kynurenine--Glyoxylate Transaminase Aadat ELISA kit Kynurenine--Oxoglutarate Aminotransferase Ii ELISA kit Kynurenine--Oxoglutarate Transaminase 2 ELISA kit Kynurenine--Oxoglutarate Transaminase Ii ELISA kit Methionine--Glyoxylate Transaminase Aadat ELISA kit AADAT ELISA kit KAT2 ELISA kit KYAT2 ELISA kit |
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Information sourced from Uniprot.org