Human 6-Phosphogluconate Dehydrogenase/PGD protein (Recombinant) (His-Tag) (STJP019240)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human 6-Phosphogluconate Dehydrogenase/PGD-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M Nacl, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 10unit/mg, in which one unit oxidize 1.0 umole of 6-phospho-D-gluconate to D-ribulose 5-phosphate per minute at pH 8.0 at 25C, in the presence of beta-NADP. |
Target Information
| Gene Symbol | PGD |
| Gene ID | 5226 |
| Uniprot ID | 6PGD_HUMAN |
| Accession Number | NP_002622 |
| Immunogen | Human |
| Immunogen Region | 1-483aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAQADIALIG LAVMGQNLIL NMNDHGFVVC AFNRTVSKVD DFLANEAKGT KVVGAQSLKE MVSKLKKPRR IILLVKAGQA VDDFIEKLVP LLDTGDIIID GGNSEYRDTT RRCRDLKAKG ILFVGSGVSG GEEGARYGPS LMPGGNKEAW PHIKTIFQGI AAKVGTGEPC CDWVGDEGAG HFVKMVHNGI EYGDMQLICE AYHLMKDV |
Additional Info
| Function | Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. |
| Protein Name | 6-Phosphogluconate Dehydrogenase - Decarboxylating |
| Database Links | Reactome: R-HSA-71336Reactome: R-HSA-9818028 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | 6-Phosphogluconate Dehydrogenase - Decarboxylating proteinPGD proteinPGDH protein |
Information sourced from Uniprot.org