| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.22 Mu m filtered solution in 20 mM Tris, 120 mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | NT5E |
| Gene ID: | 4907 |
| Uniprot ID: | 5NTD_HUMAN |
| Immunogen Region: | Trp27-Lys547 |
| Immunogen: | Recombinant Human 5 NA-Nucleotidase/NT5E/CD73 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Trp27-Lys547) of Human 5 NA-Nucleotidase/NT5E/CD73 (Accession #P21589-1) fused with a C-hFc tag at the |
| Immunogen Sequence: | WELTILHTNDVHSRLEQTSE DSSKCVNASRCMGGVARLFT KVQQIRRAEPNVLLLDAGDQ YQGTIWFTVYKGAEVAHFMN ALRYDAMALGNHEFDNGVEG LIEPLLKEAKFPILSANIKA KGPLASQISGLYLPYKVLPV GDEVVGIVGYTSKETPFLSN PGTNLVFEDEITALQPEVDK LKTLNVNKIIALGHSGFEMD KLIAQKVRGVDVVVGGHSNT FLYTGNPPSKEVPAGKYPF |
| Function | Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN. |
| Protein Name | 5'-Nucleotidase5'-Nt 5'-DeoxynucleotidaseEcto-5'-NucleotidaseImp-Specific 5'-NucleotidaseThymidylate 5'-PhosphataseCd Antigen Cd73 |
| Database Links | Reactome: R-HSA-196807Reactome: R-HSA-73621Reactome: R-HSA-74259Reactome: R-HSA-9660826 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | 5'-Nucleotidase protein5'-Nt protein5'-Deoxynucleotidase proteinEcto-5'-Nucleotidase proteinImp-Specific 5'-Nucleotidase proteinThymidylate 5'-Phosphatase proteinCd Antigen Cd73 proteinNT5E proteinNT5 proteinNTE protein |
Information sourced from Uniprot.org
