| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA.Immobilized PE anti-human CD99 Antibody at 1 Mu g/mL (100 Mu L/well) can bind Human CD99 with a linear range of 0.46-9.4 ng/mL. |
| Gene Symbol: | CD99 |
| Gene ID: | 4267 |
| Uniprot ID: | CD99_HUMAN |
| Immunogen: | Recombinant Human 12E7/CD99 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp23-Asp122) of human CD99 (Accession #NP_002405.1.) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Sequence: | DGGFDLSDALPDNENKKPTA IPKKPSAGDDFDLGDAVVDG ENDDPRPPNPPKPMPNPNPN HPSSSGSFSDADLADGVSGG EGKGGSDGGGSHRKEGEEAD |
| Function | Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes. |
| Protein Name | Cd99 Antigen12e7E2 AntigenProtein Mic2T-Cell Surface Glycoprotein E2Cd Antigen Cd99 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd99 Antigen protein12e7 proteinE2 Antigen proteinProtein Mic2 proteinT-Cell Surface Glycoprotein E2 proteinCd Antigen Cd99 proteinCD99 proteinMIC2 proteinMIC2X proteinMIC2Y protein |
Information sourced from Uniprot.org