| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | GTP cyclohydrolase 1 Positive Control for STJ501307 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Gch1 |
| Gene ID: | 14528 |
| Uniprot ID: | GCH1_MOUSE |
| Specificity: | This is positive control is recommended for use in combination with GTP cyclohydrolase 1 antibody STJ501307. |
| Post Translational Modifications | Phosphorylated. |
| Function | May positively regulate nitric oxide synthesis in endothelial cells. May be involved in dopamine synthesis. May modify pain sensitivity and persistence. |
| Peptide Name | Gtp Cyclohydrolase 1Gtp Cyclohydrolase IGtp-Ch-I |
| Database Links | Reactome: R-MMU-1474151 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Peptide Names | Gtp Cyclohydrolase 1 proteinGtp Cyclohydrolase I proteinGtp-Ch-I proteinGch1 proteinGch protein |
Information sourced from Uniprot.org