| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | GPCR GPR8 Blocking Peptide is synthetically produced from the 280-333 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Dilution Range: | WB: IHC: 1:50-1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | NPBWR2 |
| Gene ID: | 2832 |
| Uniprot ID: | NPBW2_HUMAN |
| Immunogen Region: | 280-333 |
| Immunogen: | Synthetic peptide taken within amino acid region 280-333 on human Neuropeptides B/W receptor type 2 protein. |
| Tissue Specificity | Detected at high levels in caudate nucleus, hippocampus and amygdala.at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes. |
| Function | Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. |
| Peptide Name | Neuropeptides B/W Receptor Type 2G-Protein Coupled Receptor 8 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Neuropeptides B/W Receptor Type 2 proteinG-Protein Coupled Receptor 8 proteinNPBWR2 proteinGPR8 protein |
Information sourced from Uniprot.org