| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GLUT9 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500-1:750 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Tissue Specificity | Isoform 1: Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Detected in kidney membrane (at protein level). Isoform 2: Only detected in the apical membranes of polarized renal tubular cells and placenta. Detected in kidney membrane (at protein level). |
| Function | High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules. May have a residual high-affinity, low-capacity glucose and fructose transporter activity. Transports urate at rates 45- to 60-fold faster than glucose. Does not transport galactose. May mediate small uptake of adenine but not of other nucleobases. |
| Peptide Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 9Glucose Transporter Type 9Glut-9Urate Transporter |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-5619047 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinBasolateral Cell MembraneIsoform 2: Cell MembraneApical Cell Membrane |
| Alternative Peptide Names | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 9 proteinGlucose Transporter Type 9 proteinGlut-9 proteinUrate Transporter proteinSLC2A9 proteinGLUT9 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
