| Tissue Specificity | Specifically expressed in pancreatic islet cells, in particular those of beta-cell origin. Not detected in testis, kidney, muscle, liver, lung, spleen, brain, pituitary, gastric fundus or heart. |
| Post Translational Modifications | N-glycosylated.the non-glycosylated form is more unstable and is degraded through the proteasome. |
| Function | May hydrolyze glucose-6-phosphate to glucose in the endoplasmic reticulum. May be responsible for glucose production through glycogenolysis and gluconeogenesis. |
| Peptide Name | Glucose-6-Phosphatase 2G-6-Pase 2G6pase 2Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein |
| Database Links | Reactome: R-MMU-70263 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Glucose-6-Phosphatase 2 proteinG-6-Pase 2 proteinG6pase 2 proteinIslet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein proteinG6pc2 proteinIgrp protein |
Information sourced from Uniprot.org