GIRK1 Positive Control for STJ501164 peptide (STJ504182)

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STJ504182-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : GIRK1 Positive Control for STJ501164 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Kcnj3
Gene ID: 50599
Uniprot ID: KCNJ3_RAT
Specificity: This is positive control is recommended for use in combination with GIRK1 antibody STJ501164.
Function Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel is controlled by G proteins. This receptor plays a crucial role in regulating the heartbeat.
Peptide Name G Protein-Activated Inward Rectifier Potassium Channel 1
Girk-1
Inward Rectifier K(+ Channel Kir3.1
Kga
Kgb1
Potassium Channel - Inwardly Rectifying Subfamily J Member 3
Database Links Reactome: R-RNO-1296041
Reactome: -RNO-997272
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names G Protein-Activated Inward Rectifier Potassium Channel 1 protein
Girk-1 protein
Inward Rectifier K(+ Channel Kir3.1 protein
Kga protein
Kgb1 protein
Potassium Channel - Inwardly Rectifying Subfamily J Member 3 protein
Kcnj3 protein
Girk1 protein
Kga protein

Information sourced from Uniprot.org

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