| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GIRK1 Positive Control for STJ501164 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Kcnj3 |
| Gene ID: |
50599 |
| Uniprot ID: |
KCNJ3_RAT |
| Specificity: |
This is positive control is recommended for use in combination with GIRK1 antibody STJ501164. |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat. |
| Peptide Name | G Protein-Activated Inward Rectifier Potassium Channel 1Girk-1Inward Rectifier K(+ Channel Kir3.1KgaKgb1Potassium Channel - Inwardly Rectifying Subfamily J Member 3 |
| Database Links | Reactome: R-RNO-1296041Reactome: -RNO-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | G Protein-Activated Inward Rectifier Potassium Channel 1 proteinGirk-1 proteinInward Rectifier K(+ Channel Kir3.1 proteinKga proteinKgb1 proteinPotassium Channel - Inwardly Rectifying Subfamily J Member 3 proteinKcnj3 proteinGirk1 proteinKga protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
