| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
GGCX Blocking Peptide for STJ501152 is synthetically produced from the 400-450 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
GGCX |
| Gene ID: |
2677 |
| Uniprot ID: |
VKGC_HUMAN |
| Immunogen Region: |
400-450 |
| Specificity: |
This blocking peptide is recommended for use in combination with GGCX antibody, STJ501152 |
| Immunogen: |
Synthetic peptide taken within amino acid region 400-450 on human GGCX protein |
| Function | Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalyzes gamma-carboxylation of various proteins, such as blood coagulation factors (F2, F7, F9 and F10), osteocalcin (BGLAP) or matrix Gla protein (MGP). |
| Peptide Name | Vitamin K-Dependent Gamma-CarboxylaseGamma-Glutamyl CarboxylasePeptidyl-Glutamate 4-CarboxylaseVitamin K Gamma Glutamyl Carboxylase |
| Database Links | Reactome: R-HSA-159740Reactome: R-HSA-9673240 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Vitamin K-Dependent Gamma-Carboxylase proteinGamma-Glutamyl Carboxylase proteinPeptidyl-Glutamate 4-Carboxylase proteinVitamin K Gamma Glutamyl Carboxylase proteinGGCX proteinGC protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
